Amrit Singh Wins NIH R01

December 1, 2017

Congratulations to the Singh lab whose five-year grant entitled "Regulation of RNA surveillance by the dynamic Exon Junction Complex" was recently funded by the National Institutes of Health, focusing on the interplay between RNA splicing and quality control. In human cells, an essential RNA surveillance pathway operates to suppress genetic errors and to also control normal gene activity.  Mutations in this pathway cause human developmental defects, intellectual disability and cancer.  The new NIH grant will support work in the Singh lab to investigate how and why the RNA surveillance machinery organizes this pathway into multiple parallel branches.